Analytical chemistry studies and uses instruments and methods used to separate, identify, and quantify matter.[1] In practice, separation, identification or quantification may constitute the entire analysis or be combined with another method. Separation isolates analytesQualitative analysis identifies analytes, while quantitative analysis determines the numerical amount or concentration.

Analytical chemistry consists of classical, wet chemical methods and modern, instrumental methods.[2] Classical qualitative methods use separations such as precipitationextraction, and distillation. Identification may be based on differences in color, odor, melting point, boiling point, radioactivity or reactivity. Classical quantitative analysis uses mass or volume changes to quantify amount. Instrumental methods may be used to separate samples using chromatographyelectrophoresis or field flow fractionation. Then qualitative and quantitative analysis can be performed, often with the same instrument and may use light interactionheat interactionelectric fields or magnetic fields. Often the same instrument can separate, identify and quantify an analyte.

Analytical chemistry is also focused on improvements in experimental designchemometrics, and the creation of new measurement tools. Analytical chemistry has broad applications to medicine, science and engineering.

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